Advair Inhaler (Fluticasone / Salmeterol)

Also Known as Seretide

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
50mcg/25mcg (45/21mcg) (120 doses/inhaler)
Pack Size
125mcg /25mcg (115/21mcg) (120 doses/inhaler)
Pack Size
250mcg/25mcg (230/21mcg) (120 doses/inhaler with dose counter)
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

Top Generic choice

Strength Pack Size Qty
50mcg/25mcg (45/21mcg) (120 doses/inhaler)
Pack Size
125mcg /25mcg (115/21mcg) (120 doses/inhaler)
Pack Size
250mcg/25mcg (230/21mcg) (120 doses/inhaler)
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Chemical Name FLUTICASONE (flew-TICK-uh-sone) and SALMETEROL (sal-MET-er-all)

ADVAIR helps patients breathe better. It consists of a combination of two medications (fluticasone and salmeterol) that are used to help control the symptoms of asthma and improve lung function. Fluticasone is an inhaled corticosteroid that decreases inflammation in the lungs, which can lead to asthma symptoms. Salmeterol is a long-acting beta2-agonist (LABA) used in patients with asthma and chronic obstructive pulmonary disease (COPD).

It treats both main causes of asthma symptoms-airway constriction and inflammation-to help prevent symptoms before they start. Results may vary, depending on the patient. Please note that ADVAIR is used to prevent asthma attacks and will not relieve an asthma attack that has already started.

Fact Table


Fluticasone: C22H27F3O4S1, Salmeterol: C25H37NO4




Fluticasone: Depends on formulation (e.g., nasal spray, inhaler, or topical cream); generally well-absorbed when administered correctly, Salmeterol: Low oral bioavailability due to high first-pass metabolism; more fat-soluble than short-acting beta-2 agonists like albuterol

Legal status


Chemical Name

Fluticasone / Salmeterol

Elimination half-life

Fluticasone: 10 hours, Salmeterol: 5.5 hours

Dosage (Strength)

50mcg / 25mcg (45 / 21mcg) (120 doses / inhaler),125mcg / 25mcg (115 / 21mcg) (120 doses / inhaler),250mcg / 25mcg (230 / 21mcg) (120 doses / inhaler with dose counter),50mcg/25mcg(45/21mcg)(120 doses/inhaler),125mcg /25mcg (115/21mcg)(120 doses/inhaler),250mcg/25mcg(230/21mcg)(120 doses/inhaler)


Consult a doctor



Protein binding


PubChem CID






ATC code






Routes of administration



Use ADVAIR as directed by your medical professional. Depending on your condition and medical history, your doctor may prescribe each patient a different regimen. Follow the label on the medication for exact dosing instructions. Do not change the dosage or stop taking your medication without your doctor's approval. ADVAIR is to be used only by the patient for whom it is prescribed. Do not share it with other people.

Store at room temperature in a dry place, away from heat and sunlight.


SIDE EFFECTS that may occur while taking this medicatDo not use if you are allergic to any ingredients in ADVAIR, especially fluticasone and/or salmeterol. Medical professionals advise patients to refrain from utilizing ADVAIR if they are allergic to milk proteins, if they are having an asthma attack or have severe symptoms of COPD.

To ensure your safety, please inform your medical professional if you have any of the conditions listed:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • taking any prescription, nonprescription, herbal medication or dietary supplement
  • food or drug allergies
  • heart disease or high blood pressure
  • epilepsy or any seizure disorder
  • infection (fungal, bacterial, or parasitic infection; a viral infection)
  • weak immune system
  • diabetes
  • glaucoma
  • tuberculosis
  • osteoporosis
  • a thyroid disorder
  • liver disease

Side Effects

As with most medications, ADVAIR can cause side effects. Consult your medical professional if any of these common side effects persist:

  • diarrhea
  • dizziness
  • headache
  • mild muscle or bone pain
  • nausea and/or vomiting
  • nervousness
  • throat irritation and/or swelling
  • tremors

Seek medical attention immediately if any of the following side effects occur:

  • Severe allergic reactions (rash, hives, itching, difficulty breathing, swelling of the mouth, face, lips or tongue)
  • behavior changes and/or severe mood swings
  • blurred vision or other vision changes
  • burning, numbness, or tingling
  • tightness in the chest
  • fast or irregular heartbeat
  • seizures
  • severe muscle weakness, cramps, or spasms
  • persistent bone pain
  • symptoms of high blood sugar (increased thirst, urination, or hunger)
  • insomnia
  • tiredness or weakness
  • vaginal odor or discharge
  • weight gain
  • worsening of asthma or COPD symptoms

Contact your medical professional immediately if any of the above noted symptoms apply to you. This is not a complete list of all side effects. If you require advice or have questions about side effects, contact your medical professional for more information.

Frequently Asked Questions about Advair

How do you use an Advair inhaler?

To use Advair, open the mouthpiece, load the dose, breathe in deep, hold for 10 seconds, then rinse your mouth.

Is Advair a rescue inhaler?

No, it doesn't work quickly enough for sudden asthma attacks.

Is Advair a steroid inhaler?

Yes, it contains fluticasone, a steroid that fights inflammation.

Is it OK to take Advair every day?

Yep, twice daily with the inhaler is the norm.

What to avoid when taking Advair?

Stay clear of sick folks and extra bronchodilators without your doc's okay.

What does Advair do for your lungs?

It cuts inflammation and opens up airways for easier breathing.

Can you stop Advair suddenly?

Not a good idea; quitting abruptly can bring on withdrawal symptoms.

Can Advair cause weight gain?

Some users notice a bit of weight gain, possibly due to fluid retention or metabolic changes.

Can you be on Advair long term?

Usually safe for the long haul, but there are risks like with any med.

Who should not use Advair?

If you're allergic to fluticasone, salmeterol, or milk proteins, steer clear of Advair.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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