Advair Diskus (Fluticasone / Salmeterol)

Also Known as Seretide Accuhaler

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
100/50mcg (60 doses/diskus)
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250/50mcg (60 doses/diskus)
Pack Size
500/50mcg (60 doses/diskus)
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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

Top Generic choice

Strength Pack Size Qty
250/50mcg (60 doses/multihaler)
Pack Size
500/50mcg (60 doses/multihaler)
Pack Size
100/50mcg (60 doses/rotacaps)
Pack Size
250/50mcg (60 doses/rotacaps)
Pack Size
500/50mcg (60 doses/rotacaps)
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


How to Use Your Advair Diskus Inhaler

If you have asthma or chronic obstructive pulmonary disease (COPD), your doctor may suggest the Advair Diskus inhaler. This is an easy and effective treatment that can be used to improve your breathing and the long term health of your lungs.

What is the Advair Diskus Inhaler?

Advair Diskus Generic 250 50

Advair Diskus is a dry powder inhaler that's used to treat the symptoms of asthma and bronchitis. It's a combination of two medications, fluticasone and salmeterol, which can improve lung function over the long term. These medications work in concert to treat the most troubling symptoms of asthma in the following ways:

  • Fluticasone is a corticosteroid, which reduces the inflammation in the airways,
  • Salmeterol relaxes the muscles of the airways to allow for deeper, easier breaths.

However, the Advair Diskus medication isn't designed to treat an asthma attack that's already in progress. This medication helps prevent future attacks and improves your lung strength over the long term and it doesn't work fast enough to alleviate urgent breathing difficulties. So if you're prone to asthma attacks, you still need to make sure you have your rescue inhaler with you at all times.

How to Use your Advair Diskus Inhaler

The Advair Diskus may look complicated, but it's actually really easy to use. Follow these five steps to get the full benefits of the medications:

  1. Open the mouthpiece on your Advair Diskus.
  2. Hold the inhaler so it's flat with the mouthpiece facing you and push the lever until it clicks into place.
  3. Breathe out until your lungs are empty and then inhale the medicine and hold it as long as you can before exhaling again.
  4. Close the inhaler and store it somewhere safe.
  1. Rinse your mouth to get rid of the taste.
The Advair Diskus inhaler should never be used in a breathing emergency. Make sure you have a rescue inhaler with you at all times if you're prone to asthma attacks and seek immediate professional help if the rescue inhaler doesn't relieve the breathing problem.  

Advair Diskus Doses

Advair Diskus 250/50

There are a few different types of Advair Diskus inhalers which have the same combination of medications, but in different strengths. Advair Diskus 250/50 is mostly used to treat chronic obstructive pulmonary disease (COPD). It contains 250 mcg fluticasone propionate and 50 mcg salmeterol.

  Advair Diskus 100/50 contains a lower dose of fluticasone propionate (100 mcg) and the same dose of salmeterol. If you aren't sure which to buy, make sure you discuss these options with your doctor before making a purchase. They'll help you to find the right Advair Diskus doses for your condition and life circumstances.

  The Advair Diskus should be taken twice a day with roughly 12 hours between doses. You should also ensure that you take your Advair Diskus doses at the same time each day for the best effects. It's safe for anyone over the age of four who suffers from chronic asthma symptoms to use.

  ADVAIR DISKUS 250/50 (also known as Advair 250 50) is a twice-daily prescription medicine used long term to treat chronic obstructive pulmonary disease (COPD) for better breathing and fewer flare-ups.

Advair Diskus Price

best advair diskus price click on the product drop down above and select to product size you are looking for to add to your cart.

From time to time as a Canada Drugs Direct client you may also receive advair diskus coupon codes to save even more on this product.


Advair Diskus How to Use

Follow these steps every time you use ADVAIR DISKUS. If you have any questions make sure to consult your doctor.

Step 1. Open your ADVAIR DISKUS.
Step 2. Slide the lever until you hear it click.
Step 3. Inhale your medicine.
Step 4. Close the DISKUS. (When you are ready to take your next dose, repeat Steps 1 through 4.)
Step 5. Rinse your mouth.

For more information on how to use Advair Diskus consult your doctor or read this guide.

Fact Table







Legal status

RX Only

Chemical Name

Fluticasone / Salmeterol

Elimination half-life

9-11 hours

Dosage (Strength)

100/50mcg (60 doses/diskus), 250/50mcg (60 doses/diskus), 500/50mcg (60 doses/diskus)


Consult a doctor


Advair Diskus

Protein binding


PubChem CID






ATC code






Routes of administration



Who Shouldn't Take this Medication?

Before you start taking any new medication you need to discuss it with your doctor. You can help them to make the right diagnosis and prescribe the right treatment by giving them all the relevant information. Firstly, make sure that they're aware of any allergies you have, including any food allergies, to avoid an allergic reaction.

The second thing you should share with your doctor is a list of any medications, prescription and non-prescription, that you're taking. The medications in the Advair Diskus can react with other medications, so this is particularly important for your safety. Disclosing this information will also help to ensure that the Advair Diskus medications work properly.

And finally, make sure your doctor has your complete medical history, especially any past history of infections that could change the way this medication interacts with your body. By sharing all this information with your doctor, you will be doing your part to keep yourself safe and healthy while you're trying the Advair Diskus.

Side Effects

Potential Side Effects

There are side effects that you must be aware of with any medication. Though most people use the Advair Diskus without any serious side effects, you still need to be aware of problems you may encounter. The most common potential side effects of this medication include:

  • Dry throat
  • Body aches or pain
  • Sneezing or a runny nose
  • Stomach upsets
  • Headache
  • Choking
  • Voice changes, such as hoarseness
  • Congestion
  • High-pitched noises when breathing
  • Difficlity swallowing
  • High blood pressure

If you notice any of the above symptoms make sure you discuss your options with your doctor.

The following are a list of less common but more serious symptoms that can reslit from Advair Diskus medications. If you notice any of the following, make sure you discontinue your medication and see a professional as soon as possible:

  • Chest pain
  • Tremors
  • Allergic reactions such as swelling or rash
  • Infections in the mouth or throat
  • Fast or irregliar heartbeat
  • Breathlessness immediately after your dose
  • Increased anxiety
  • Vision problems
  • Increased susceptibility to infections

Frequently Asked Questions about Advair

Does Advair have a steroid in it?

Yes, Advair has fluticasone (a steroid) and salmeterol (a bronchodilator). Fluticasone helps reduce inflammation, while salmeterol helps relax airway muscles.

What does Advair do for your lungs?

Advair aids in preventing asthma attacks and COPD flare-ups. It eases breathing by relaxing muscles in the airways.

What to avoid when taking Advair?

Avoid using another medicine with a long-acting beta-agonist (LABA) alongside Advair. It doesn't replace a rescue inhaler for sudden symptoms. Remember to rinse your mouth after using it to prevent fungal infections.

Who shouldn't take Advair?

Don't use Advair if allergic to fluticasone, salmeterol, or milk proteins. Severe milk protein allergy is a reason to avoid Advair.

Is it OK to take Advair everyday?

Yes, Advair is for daily use to manage asthma or COPD.

Can you stop Advair suddenly?

Check with your doctor before stopping Advair; sudden cessation isn't recommended.

Can Advair cause weight gain?

Advair doesn't typically lead to significant weight gain.

Is it bad to take Advair long term?

Using steroids (like fluticasone) for a long time may lead to bone loss (osteoporosis). Discuss risks with your doctor.

What is the black box warning for Advair?

Advair has a black box warning because of a higher risk of asthma-related death. It's not the first choice for asthma treatment.

Are there mental side effects to Advair?

While rare, some individuals may experience mental effects. Consult your doctor if concerned.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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