Adlyxin (Lixisenatide)

Also Known as Adlyxine

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Adlyxin (Lixisenatide) is a once-daily injectable medication prescribed for adults with type 2 diabetes mellitus. As a glucagon-like peptide-1 (GLP-1) receptor agonist, Adlyxin works by helping the body produce more insulin and slowing down the emptying of the stomach. It is used together with a balanced diet and regular exercise to manage blood sugar levels.


Fact Table

Formula

C215H347N61O65S

License

US DailyMed, EU EMA

Bioavailability

approximately 2.17%

Legal status

Rx-only

Chemical Name

Lixisenatide

Elimination half-life

3-4 hours

Dosage (Strength)

10 mcg, 20 mcg

Pregnancy

Not recommended for use during pregnancy

Brands

Adlyxin

Protein binding

approximately 55%

PubChem CID

90472060

MedlinePlus

a617005

ChEBI

85662

ATC code

A10BJ03

DrugBank

DB09265

KEGG

D09729

Routes of administration

Subcutaneous

Directions

The initial dose of Adlyxin is 10 mcg, administered under the skin (subcutaneously) once daily for 14 days. Maintenance therapy begins on day 15 with an increased dosage of 20 mcg once daily. It is usually prescribed to be injected within one hour of the first meal of the day. Adlyxin can be injected into the skin of the thigh, upper arm, or stomach area. Always follow your healthcare provider's instructions and adhere to any special dietary guidelines given.

Ingredients

Adlyxin is an injectable prescription medication containing the active ingredient lixisenatide.

Contraindications

Avoid using Adlyxin if you have a severe hypersensitivity or allergy to lixisenatide or any ingredient in Adlyxin.

Cautions

  • Before taking Adlyxin, it is important to inform your doctor about:
    • Any medications you take, including prescription drugs, over-the-counter medicines, and herbal supplements, especially other diabetes medications, birth control pills, or antibiotics.
    • Any medical conditions, including pancreatitis, gallbladder problems, kidney disease, stomach problems, or a history of alcoholism.
    • If you are pregnant or plan to become pregnant
    • If you are breastfeeding or planning to breastfeed
  • Using Adlyxin with medicines like sulfonylurea or insulin could increase your risk of low blood sugar (hypoglycemia). Symptoms may include headaches, dizziness, or weakness. Consult your healthcare provider as you may need to adjust your other medications.
  • If you have pre-existing kidney conditions, side effects such as diarrhea and nausea from Adlyxin could worsen your condition due to dehydration.
  • Gallbladder issues have been reported by some people taking Adlyxin. Look out for symptoms like abdominal pain or fever, and seek immediate medical attention if these occur.
  • Regular check-ups may be necessary when using Adlyxin to keep track of blood sugar levels and the health of your kidneys and gallbladder.
  • Never share the Adlyxin pen between patients, even if the needle has been changed.
  • Some people may develop antibodies to lixisenatide, which can affect blood sugar control. If this occurs, consider alternative antidiabetic treatments.

Side Effects

As with most medications, some side effects can occur during the use of Adlyxin. The most commonly reported side effects include nausea, vomiting, headache, diarrhea, dizziness, and hypoglycemia.

Monitor these side effects and discuss them with a healthcare professional if they become severe or persistent. In many cases, a healthcare professional can provide advice on ways to prevent or reduce some of these side effects.

Serious side effects may include allergic reactions, kidney problems, and gallbladder problems. Seek immediate medical help if you experience severe side effects, such as difficulty breathing, swelling of the face or throat, severe pain in the upper stomach, rapid heartbeat, or trouble swallowing.

References:

  1. Adlyxin Prescribing Information. Bridgewater, NJ: Sanofi-Aventis; 2022.
  2. Lixisenatide Injection Drugs, Herbs and Supplements. Bethesda, MD: National Library of Medicine; 2017.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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