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Aczone Gel (Dapsone)

Prescription medicineOnly Available By Prescription

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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Aczone is a prescription gel used to treat acne vulgaris. Acne vulgaris is the same condition that affects many teenagers and adults. The symptoms include the formation of blackheads, whiteheads, and other types of pimples on the face. The pimples may burn, be painful, and may produce pus. They may also be present on other parts of the body.

It is not known how Aczone works in the treatment of acne vulgaris. Aczone contains an antibacterial agent and may prevent the growth of bacteria that clog pores on the skin. 

Fact Table






70 to 80%

Legal status


Chemical Name


Elimination half-life

20 to 30 hours

Dosage (Strength)



Consult Doctor



Protein binding

70 to 90%

PubChem CID






ATC code






Routes of administration

By mouth


Use Aczone exactly as directed by your healthcare provider. It should only be used externally and never ingested or on sensitive areas of skin.

Aczone gel directions: apply a small amount of Aczone once daily to the entire face and other affected body areas.

Do not mix Aczone with other topical medications or over-the-counter products.


Dapsone is the active ingredient in Aczone.

Inactive ingredients include diethylene glycol monoethyl ether, methylparaben, acrylamide/sodium acryloyldimethyl taurate copolymer, isohexadecane, polysorbate 80, and purified water. 

Do not use Aczone if you have an allergy to any of the ingredients listed above.


Common drug-drug interactions with Aczone may include:

  • Anesthetics
  • Benzoyl peroxide
  • Methemoglobinemia
  • Nitric oxide
  • Prilocaine
  • Sodium nitrite
  • Trimethoprim

Tell your doctor or pharmacist if you start taking any new medications while you are on Aczone. 


Use caution if you have a condition called glucose-6-phosphate dehydrogenase (G6PD). Using this medication with G6PD deficiency may increase your risk of hemolysis and anemia.

Aczone has been known to cause methemoglobinemia in certain patients.

Side Effects

Common Aczone gel side effects may include:

  • Application site rash
  • Erythematous rash
  • Facial edema
  • Lip edema
  • Periorbital swelling
  • Sinusitis
  • Skin rash


Aczone [package insert]. Irvine, CA: Allergan; 2016.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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