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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Actimmune (interferon gamma-1b) is a recombinant human interferon gamma indicated for the treatment of chronic granulomatous disease (CGD) and severe malignant osteopetrosis (SMO). In CGD, it reduces the frequency of serious infections by enhancing the microbial activity of phagocytes. In SMO, it is used to delay disease progression by modulating immune function and bone resorption. Actimmune exerts immunomodulatory, antiviral, and antiproliferative effects by inducing the expression of immune-regulatory genes and enhancing oxidative metabolism in phagocytes.
Fact Table | |
Formula | C769H1201N215O224S9 |
License | US FDA (1990) |
Bioavailability | Subcutaneous: ~33% |
Legal status | Prescription only |
Chemical Name | Interferon gamma-1b |
Elimination half-life | ~5 hours |
Dosage (Strength) | 100 mcg (2 million IU)/0.5 mL injection solution |
Pregnancy | Category C – Risk not ruled out |
Brands | Actimmune |
Protein binding | Not extensively bound (protein therapeutic) |
PubChem CID | 16131143 |
MedlinePlus | a604018 |
ChEBI | 59578 |
ATC code | L03AB05 |
DrugBank | DB00033 |
KEGG | D02632 |
Routes of administration | Subcutaneous injection |
Actimmune is administered by subcutaneous injection.
Active ingredient: interferon gamma-1b Inactive ingredients: mannitol, sodium succinate hexahydrate, succinic acid, polysorbate 20, and sterile water for injection (diluent supplied separately). The solution is preservative-free.
Actimmune is contraindicated in patients with:
Caution should be exercised in patients with pre-existing cardiac conditions, as transient flu-like symptoms (fever, chills) may exacerbate underlying disease. Hepatic function should be monitored due to the potential for elevated liver enzymes. Neurological effects including spasticity and gait disturbance have been reported, especially in patients with pre-existing central nervous system disorders. Use with caution in patients with bone marrow suppression or cytopenias. Regular monitoring of complete blood counts and liver function tests is recommended.
Common side effects may include:
Serious adverse effects may include hepatotoxicity, bone marrow suppression, neuropsychiatric symptoms, and hypersensitivity reactions.