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Actigall (Ursodiol)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


ACTIGALL (Ursodiol) is a medication prescribed for a variety of uses, including the treatment and prevention of gallstones.

The gallbladder produces bile, which is a digestive fluid that helps to metabolize fats and fatty acids. Gallstones are hardened deposits of bile that form in the gallbladder. They may be present without causing symptoms but can cause symptoms when they block the bile duct.

ACTIGALL works in the liver and reduces the amount of cholesterol that it releases. By decreasing cholesterol secretion, bile is less likely to form into bile stones.

Fact Table







Legal status


Chemical Name


Elimination half-life

Not Available

Dosage (Strength)



Consult Doctor


Actigall, Urso

Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


Take ACTIGALL exactly as prescribed by your doctor.

If you are taking ACTIGALL for gallstone prevention, take 300 mg by mouth twice daily.

If you are taking ACTIGALL for gallstone treatment, take 8-10 mg/kg/day in two or three divided doses. Your healthcare provider will calculate the correct dosage.


The active ingredient in ACTIGALL is ursodiol.

Ursodiol is the name of ACTIGALL generic.


ACTIGALL has many drug interactions. Tell your doctor or pharmacist if you are taking any of the following:

  • Aluminum hydroxide
  • Bile acid sequestrants
  • Estrogen products (oral contraceptives)
  • Fibric acid derivatives
  • Nitrendipine
  • Sincalide


Tell your doctor if you have a history of liver disease before taking ACTIGALL. If so, your liver will need to be monitored during the first 3 months of treatment and every 6 months thereafter.

It may take several months of therapy for gallstones to dissolve if ACTIGALL is being used for dissolution.

Side Effects

Common adverse effects from ACTIGALL may include:

  • Alopecia
  • Arthritis
  • Back pain
  • Bronchitis
  • Cholecystitis
  • Constipation
  • Cough
  • Diarrhea
  • Dizziness
  • Dyspepsia
  • Headache
  • Hyperglycemia
  • Hypersensitivity reaction
  • Increased kidney enzymes
  • Leukopenia
  • Musculoskeletal pain
  • Nausea
  • Peptic ulcer
  • Pharyngitis
  • Skin rash
  • Thrombocytopenia
  • Upper respiratory tract infection
  • Urinary tract infection
  • Viral infection
  • Vomiting

If you are looking for a low ACTIGALL cost, you can buy ACTIGALL online from Canada Drugs Direct with a valid prescription from your doctor.


Actigall [package insert]. Madison, NJ: Allergan; 2018.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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