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Aciphex (Rabeprazole)

Also Known as Pariet,Parit

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Chemical Name: RABEPRAZOLE (ra-BE-pray-zole) Aciphex is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid). Aciphex may also be given with an antibiotic to prevent gastric ulcer caused by infection with helicobacter pylori (H. pylori). ACIPHEX is not intended for immediate relief of heartburn symptoms.

Fact Table




FDA approved


Not completely absorbed (about 52% after oral administration)

Legal status

Prescription only (US: Rx-only)

Chemical Name


Elimination half-life

Approximately 1-2 hours

Dosage (Strength)

Tablets: 20 mg, 10 mg

Pregnancy advice

Category B (No evidence of risk in studies)


Aciphex, Pariet, others

Protein binding


PubChem CID






ATC code






Routes of administration



Use ACIPHEX exactly as directed by your healthcare professional. Do not change your doses or dosing schedule without consulting your healthcare professional. Generally, ACIPHEX is prescribed for 4 to 8 weeks only. Your doctor may recommend a second course of treatment if you need additional healing time.

ACIPHEX may be taken with or without food. It is recommended to take this medication with a full glass (8 ounces) of water. Do not crush, break, or chew - swallow the tablet whole. Breaking or tampering with the tablet may alter the effects of the medication. Take this medication for the full prescribed length of time.


Not all medications work effectively for every patient, therefore it is important to consult your doctor about any health conditions, especially liver disease, if you have low magnesium levels in your blood, pregnant or planning on becoming pregnant and/or if you are breastfeeding.

Do not use ACIPHEX if you are allergic to rabeprazole or similar medications such as Prevacid, Nexium, Prilosec, Zegerid or Protonix.

Taking this medication may increase your risk of bone fracture in the hip, wrist, or spine. This effect mostly appeared in patients who took the medication over a long period of time or at high doses, (age 50+). It is unclear whether ACIPHEX is the actual cause of an increased risk of fracture however patients should inform their healthcare professional if they have osteoporosis or osteopenia.

Side Effects

All medication has side effects which may vary from serious to mild. Patients should remember that their healthcare professional has prescribed ACIPHEX because they feel the benefits of taking this medication outweigh the risk of side effects.

Contact your healthcare professional immediately if you have serious side effects, including:

  • Dizziness or confusion
  • Fast or uneven heart rate
  • Jerking muscle movements
  • Feelings of jitteriness
  • Muscle cramps, weakness or limp feeling
  • Cough or choking feeling
  • Seizure or convulsions
Less serious ACIPHEX side effects may include:
  • Severe headache
  • Upset stomach or diarrhea
  • Insomnia
  • Nervousness
  • Rash or itchy skin
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of any serious allergic reactions such as rash, itching/swelling, severe dizziness and/or trouble breathing.

This is not a complete list of possible side effects. If you notice other effects, contact your healthcare professional immediately.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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