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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
A535 Rub is an over-the-counter topical analgesic indicated for the temporary relief of muscle and joint pain associated with strains, sprains, arthritis, and backaches. It contains counterirritant and analgesic agents that produce a warming or cooling sensation to help alleviate pain by distracting from deeper muscular discomfort. A535 Rub is available in several formulations, including regular, ultra-strength, and no-odour versions, designed for external use only. It is a commonly used product in sports medicine and home care settings for short-term symptomatic pain management.
| Fact Table | |
| Formula | C8H8O3 (methyl salicylate), C10H20O (menthol) |
| License | Health Canada; OTC |
| Bioavailability | Topical absorption; systemic bioavailability is minimal |
| Legal status | Over-the-counter (OTC) |
| Chemical Name | Methyl salicylate; Menthol; +/- Camphor/Capsaicin |
| Elimination half-life | Varies; ~2-3 hours (methyl salicylate if absorbed) |
| Dosage (Strength) | Methyl salicylate 15–30%, Menthol 5–10% (varies by product) |
| Pregnancy | Use with caution; avoid large areas or prolonged use |
| Brands | A535 Rub, Rub A535, Antiphlogistine |
| Protein binding | Not significant topically; systemic data limited |
| PubChem CID | Methyl salicylate: 4133; Menthol: 1254 |
| MedlinePlus | a682775 (methyl salicylate) |
| ChEBI | Methyl salicylate: 6825; Menthol: 15408 |
| ATC code | M02AC (topical analgesics) |
| DrugBank | Methyl salicylate: DB09555; Menthol: DB00825 |
| KEGG | Methyl salicylate: D02366; Menthol: D08173 |
| Routes of administration | Topical |
Apply A535 Rub to the affected area up to 3–4 times daily. Massage gently until the product is fully absorbed. Wash hands thoroughly after application unless treating the hands. Avoid use on broken or irritated skin, and do not bandage tightly or use with heating pads, as this may increase the risk of skin irritation or burns. If symptoms persist beyond 7 days or worsen, discontinue use and consult a healthcare provider. Use in children under 12 years of age should be supervised by a healthcare professional.
The active ingredients vary slightly by formulation but typically include:
Methyl salicylate (10–30%) – topical analgesic and counterirritant
Menthol (2–10%) – cooling counterirritant
Camphor (3–10%) – warming counterirritant
Inactive ingredients may include:
Polyethylene glycol, stearic acid, lanolin, fragrance (in scented formulas), and other emulsifiers or stabilizers
A535 Rub is contraindicated in individuals with:
Known hypersensitivity to salicylates, menthol, camphor, or any ingredient in the product
Existing skin conditions such as eczema or dermatitis in the area of application
Aspirin or NSAID allergies
Use caution in individuals with asthma or aspirin sensitivity due to the presence of methyl salicylate. The product is for external use only and should not be ingested or applied to mucous membranes. Avoid contact with eyes; if contact occurs, rinse thoroughly with water. Discontinue use if skin irritation, rash, or burning occurs. Not recommended during pregnancy or breastfeeding unless advised by a healthcare provider. Keep out of reach of children, as accidental ingestion may be harmful or fatal.
Possible side effects include:
Localized redness or burning sensation
Mild skin irritation or rash
Rare: allergic contact dermatitis or hypersensitivity reaction
Very rare: salicylate toxicity with overuse or accidental ingestion
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phone 1-888-904-8467 or email info@canadadrugsdirect.com.
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