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Soliqua 100/33 (Insulin)

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


SOLIQUA 100/33 (Insulin glargine and lixisenatide) is a combination drug product prescribed for people with type 2 diabetes mellitus. SOLIQUA 100/33 should be used in addition to diet and exercise to improve blood sugar control.


The starting dose of SOLIQUA 100/33 is determined by your doctor and can be:

  • 15 units insulin glargine and 5 micrograms lixisenatide
  • 30 units insulin glargine and 10 micrograms lixisenatide

The maximum daily dosage is 60 units insulin glargine and 20 micrograms lixisenatide.

Inject SOLIQUA 100/33 under the skin once daily at the same time each day.


SOLIQUA 100/33 contains a mixture of two medications. The drugs are delivered with a single injection.

The first medication in SOLIQUA is insulin glargine, long-acting insulin that lasts for about 24 hours in most people.

The second medication is a GLP-1 receptor agonist called lixisenatide, which increases the release of endogenous insulin from the pancreas.


SOLIQUA 100/33 slows down the movement of certain drugs through the gastrointestinal tract. Take the following medications at least one hour before or 11 after SOLIQUA 100/33:

  • Acetaminophen (Tylenol)
  • Antibiotics
  • Oral contraceptives

Certain medications can affect the blood sugar of people with diabetes. Use caution if you are taking any of the following:

  • Alcohol
  • Atypical Antipsychotics
  • Corticosteroids
  • Disopyramide
  • Diuretics
  • Estrogens/Progesterones
  • Fibrates
  • Fluoxetine
  • Isoniazid
  • Lithium
  • Monoamine Oxidase Inhibitors (MAOIs)
  • Niacin
  • Oral antidiabetic agents
  • Pentoxifylline
  • Phenothiazine derivatives
  • Pramlintide
  • Propoxyphene
  • Protease inhibitors
  • Salicylates
  • Somatostatin Analogues
  • Somatropin
  • Sulfonamide Antibiotics
  • Sympathomimetic agents
  • Thyroid replacement medication

The following drugs can mask the symptoms of hypoglycemia:

  • Beta-blockers
  • Clonidine
  • Guanethidine
  • Reserpine


Tell your doctor if you have a history of pancreatitis.

Do not use an additional GLP-1 receptor agonist agent while using SOLIQUA 100/33.

SOLIQUA 100/33 pens should never be shared with multiple patients.

Monitor blood sugar regularly to detect and treat hypoglycemia, which can be life-threatening.

Your doctor should monitor potassium levels, kidney function, and liver function while taking SOLIQUA 100/33.

Side Effects

The most common adverse reactions with SOLIQUA 100/33 may include:

  • Allergic reactions
  • Diarrhea
  • Hypoglycemia
  • Nasopharyngitis
  • Nausea
  • Upper respiratory tract infections


Soliqua 100/33 [package insert] Bridgewater, NJ: Sanofi-Aventis; 2016

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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