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Myfortic (Mycophenolic Acid)

Prescription medicineOnly Available By Prescription

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Myfortic is an immunosuppressant that is taken to prevent organ rejection in adult patients who have received a kidney transplant and in children 5 years of age or older who are at least 6 months post kidney transplant. 

Mycophenolic acid is the generic name for Myfortic.

Fact Table




US DailyMed, EU EMA


72% (sodium), 94% (mofetil)

Legal status


Chemical Name

Mycophenolic acid

Elimination half-life

17.9±6.5 hours

Dosage (Strength)



Not Recommended



Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


Myfortic should be used with cyclosporine and corticosteroids

Myfortic is available in tablets of 180 mg and 360 mg strengths. The tablets should not be crushed, chewed, or cut. Swallow the tablets whole. 

Myfortic Dosage:

Adults: 720 mg by mouth two times daily without food. Take at least one hour before or two hours after eating.

Children at least 5 years old and at least 6 months post kidney transplant: 400 mg/m2 by mouth two times daily. Do not exceed the adult dose.


The active ingredient contained in Myfortic tablets is mycophenolic acid as mycophenolate sodium.


Talk to your doctor about any allergies you may have. 

You should not take Myfortic (mycophenolic acid) if you are allergic to mycophenolate sodium, mycophenolic acid, mycophenolate mofetil, or to any of the other ingredients in Myfortic. Myfortic can cause reactions such as a rash, itching, low blood pressure, and chest pain in patients with a known hypersensitivity to Myfortic, mycophenolate sodium, mycophenolic acid, mycophenolate mofetil, or any of its excipients. 



See full prescribing information for complete boxed warning

  • Use during pregnancy is associated with increased risks of pregnancy loss and congenital malformations. Avoid if safer treatment options are available. Females of reproductive potential must be counseled regarding pregnancy prevention and planning. 
  • Increased risk of development of lymphoma and other malignancies, particularly of the skin, due to immunosuppression. 
  • Increased susceptibility to bacterial, viral, fungal, and protozoal infections, including opportunistic infections. 
  • Only physicians experienced in immunosuppressive therapy and management of organ transplant patients should prescribe Myfortic. 
  • Before you start taking Myfortic, tell your doctor about all the medications you take. Myfortic can interact with certain medications that may lead to serious reactions. 
  • You should not use Myfortic delayed release tablets and mycophenolate mofetil tablets and capsules interchangeably. 
  • Once you are prescribed and purchase Myfortic, Myfortic can increase your risk for lymphomas and malignancies, especially of the skin. Your sun exposure should be limited. If you go outside, be sure you protect your skin with protective clothing and a broad-spectrum sunscreen with a high protection factor.
  • Let your doctor know about any viral infections you may have, including tuberculosis, hepatitis B, or hepatitis C. Patients who take Myfortic are at an increased risk for new or reactivated infections. Seek medical attention right away if you develop a fever, muscle aches, appetite changes, vomiting, or rash. 
  • Blood dyscrasia such as pure red cell aplasia may occur during treatment with Myfortic. Monitoring for neutropenia or anemia should be conducted in patients receiving Myfortic.
  • Tell your doctor if you have a digestive system disease. Gastrointestinal bleeding, intestinal perforations, duodenal ulcers, and gastric ulcers may occur during treatment with Myfortic. Seek immediate medical care if you have blood in your stools or vomit.
  • Talk to your doctor before you receive any vaccinations. Live attenuated vaccines should not be given in patients who take Myfortic.
  • Tell your doctor if you have a rare hereditary deficiency of hypoxanthine-guanine phsphoribosyl-transferase (HGPRT), such as Lesch-Nyhan syndrome or Kelley-Seegmiller syndrome. Myfortic can exacerbate the symptoms of these diseases; therefore, Myfortic should be avoided in these patients.
  • Do not donate blood during Myfortic therapy and for at least 6 weeks after you stop taking Myfortic because a woman who can become pregnant or a woman who is pregnant may receive your blood.
  • Do not donate semen during Myfortic therapy or for 90 days after stopping Myfortic.
  • Sexually active patients and their partners should use an effective contraceptive during treatment with Myfortic and for at least 90 days after discontinuation of Myfortic. 
  • Tell your doctor if you are pregnant, might be pregnant, or planning to become pregnant. Myfortic is associated with an increased risk of pregnancy loss and congenital malformations. Use safer treatment options if possible. 
  • Tell your doctor if you breastfeed or plan to breastfeed. There is little data regarding the effects of Myfortic during breastfeeding are not known. 

Side Effects

Myfortic can cause side effects and some may become serious. Contact your doctor immediately if you develop severe side effects or side effects that won't go away or become bothersome. Common side effects of Myfortic include: 

  • Anemia
  • Constipation
  • Diarrhea
  • Leukopenia 
  • Indigestion
  • Nausea
  • Vomiting
  • Problems sleeping
  • Urinary tract infection
  • Post-procedure pain 


  1. Myfortic. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2020.
  2. Mycophenolic acid (Myfortic). GoodRx. Accessed November 23, 2021.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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